Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Nr4a2  nuclear receptor subfamily 4, group A, member 2   (Synonyms: HZF-3, Nurr1, RNR-1)
Results	Reference
1	J:95539 Calo L, Spillantini M, Nicoletti F, Allen ND, Nurr1 co-localizes with EphB1 receptors in the developing ventral midbrain, and its expression is enhanced by the EphB1 ligand, ephrinB2. J Neurochem. 2005 Jan;92(2):235-45
1	J:309996 Dumas S, Wallen-Mackenzie A, Developmental Co-expression of Vglut2 and Nurr1 in a Mes-Di-Encephalic Continuum Preceeds Dopamine and Glutamate Neuron Specification. Front Cell Dev Biol. 2019;7:307
1	J:311153 Gahankari A, Dong C, Bartoletti G, Galazo M, He F, Deregulated Rac1 Activity in Neural Crest Controls Cell Proliferation, Migration and Differentiation During Midbrain Development. Front Cell Dev Biol. 2021;9:704769
1	J:182759 Lahti L, Peltopuro P, Piepponen TP, Partanen J, Cell-autonomous FGF signaling regulates anteroposterior patterning and neuronal differentiation in the mesodiencephalic dopaminergic progenitor domain. Development. 2012 Mar;139(5):894-905
1	J:199477 Lewis AE, Vasudevan HN, O'Neill AK, Soriano P, Bush JO, The widely used Wnt1-Cre transgene causes developmental phenotypes by ectopic activation of Wnt signaling. Dev Biol. 2013 Jul 15;379(2):229-34
1*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1	J:73971 Ponnio T, Burton Q, Pereira FA, Wu DK, Conneely OM, The nuclear receptor Nor-1 is essential for proliferation of the semicircular canals of the mouse inner ear. Mol Cell Biol. 2002 Feb;22(3):935-45
1*	J:215514 Saulnier A, Keruzore M, De Clercq S, Bar I, Moers V, Magnani D, Walcher T, Filippis C, Kricha S, Parlier D, Viviani L, Matson CK, Nakagawa Y, Theil T, Gotz M, Mallamaci A, Marine JC, Zarkower D, Bellefroid EJ, The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals. Cereb Cortex. 2013 Nov;23(11):2552-67
1*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:147559 Thuret S, Alavian KN, Gassmann M, Lloyd CK, Smits SM, Smidt MP, Klein R, Dyck RH, Simon HH, The neuregulin receptor, ErbB4, is not required for normal development and adult maintenance of the substantia nigra pars compacta. J Neurochem. 2004 Dec;91(6):1302-11
1	J:73864 Wallen A A, Castro DS, Zetterstrom RH, Karlen M, Olson L, Ericson J, Perlmann T, Orphan nuclear receptor Nurr1 is essential for Ret expression in midbrain dopamine neurons and in the brain stem. Mol Cell Neurosci. 2001 Dec;18(6):649-63
1	J:58939 Wallen A, Zetterstrom RH, Solomin L, Arvidsson M, Olson L, Perlmann T, Fate of mesencephalic AHD2-expressing dopamine progenitor cells in NURR1 mutant mice. Exp Cell Res. 1999 Dec 15;253(2):737-46
1	J:161774 Wang S, Turner EE, Expression of dopamine pathway genes in the midbrain is independent of known ETS transcription factor activity. J Neurosci. 2010 Jul 7;30(27):9224-7
1	J:204963 Yang S, Edman LC, Sanchez-Alcaniz JA, Fritz N, Bonilla S, Hecht J, Uhlen P, Pleasure SJ, Villaescusa JC, Marin O, Arenas E, Cxcl12/Cxcr4 signaling controls the migration and process orientation of A9-A10 dopaminergic neurons. Development. 2013 Nov;140(22):4554-64
1	J:289516 Yang S, Toledo EM, Rosmaninho P, Peng C, Uhlen P, Castro DS, Arenas E, A Zeb2-miR-200c loop controls midbrain dopaminergic neuron neurogenesis and migration. Commun Biol. 2018;1:75
1	J:39661 Zetterstrom RH, Solomin L, Jansson L, Hoffer BJ, Olson L, Perlmann T, Dopamine neuron agenesis in Nurr1-deficient mice [see comments]. Science. 1997 Apr 11;276(5310):248-50
1*	J:37081 Zetterstrom RH, Solomin L, Mitsiadis T, Olson L, Perlmann T, Retinoid X receptor heterodimerization and developmental expression distinguish the orphan nuclear receptors NGFI-B, Nurr1, and Nor1. Mol Endocrinol. 1996 Dec;10(12):1656-66